Passed by Congress in 1966, the Animal Welfare Act (AWA) sets general standards for humane care and treatment that must be provided for certain animals that are bred for commercial sale, sold sight unseen (Internet sales), exhibited to the public, used in biomedical research, or transported commercially. Congress assigned the U.S. Department of Agriculture (USDA) the responsibility for enforcing the AWA. The Animal and Plant Health Inspection Service (APHIS) is the agency within USDA responsible for ensuring this occurs. APHIS has published the Animal Welfare Act and Animal Welfare Regulations, known as the “Blue Book,” as a tool to improve compliance among our licensees and registrants and to enhance the consistency of inspections by our field inspectors. The Blue Book consolidates into one source the AWA and the applicable regulations and standards.