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E-book Evidence-based Positron Emission Tomography : Summary of Recent Meta-analyses on PET

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Penilaian

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The wide and feasible availability of positron emitters radionuclides is a prerequisite for suc-cessful application on a routine basis. Fluorine-18 and Gallium-68 are the most used in a clinical setting, so far. Due to its versatility, 18F-Fluorodeoxyglucose (FDG), namely a radio-labelled analogue of glucose, is the by far most widely used PET radiopharmaceutical world-wide. FDG is very useful to detect malignant tumours characterized by increased glucose metabolism. However, FDG remains a non-specific tracer and its uptake is also been observed in many benign conditions, such as infective and inflammatory processes. Therefore, over the last decade, there is a growing interest in researching and using new radiopharmaceuticals, such as radiolabelled amino acids, nucleoside deriva-tives, choline derivatives, nitroimidazole deriva-tives and peptides, able to carefully target specific biomarkers. These new generation radiopharma-ceuticals allow the analysis of several molecular pathways in tumour biology including metabo-lism, proliferation, oxygen delivery and protein synthesis as well as receptor and gene expression (Tables 1.4, 1.5 and 1.6). This open access book summarizes the findings of recent evidence-based articles (meta-analyses) on the use of positron emission tomography (PET) for various clinical indications. It is divided into five main sections, starting with an introduction to PET and meta-analysis. In turn, the second part addresses evidence-based PET in oncology, providing a broad overview of its use for different types of tumours. The remaining sections are focused on the use of PET in cardiology, in infectious and inflammatory diseases, and in neurology, respectively. Given its scope and the wealth of information it provides, the book will be an invaluable tool for clinicians with various specialties, as well as international scientific societies interested to the recent evidence-based data about PET.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

616.0757 TRE e

Penerbit

Switzerland : Springer Nature., 2020

Deskripsi Fisik

138 hlm

Bahasa

English

ISBN/ISSN

9783030477011

Klasifikasi

616.0757

Tipe Isi

text

Tipe Media

computer

Tipe Pembawa

online resource

Edisi

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Subjek

Radiological Diagnosis

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

Lampiran Berkas

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