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E-book A Holter for Parkinson’s Disease Motor Symptoms : STAT-On

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Penilaian

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Parkinson’s disease (PD) is the second most frequent neurodegenerative disorder, with approximately 6.1 million people who live with PD in 2016 worldwide [1]. For several reasons that are not yet fully understood, the prev­alence and incidence are expected to increase in the next years. According to the World Health Organization, globally, disability and death due to PD are increasing faster than for any other neurological disorder [2]. There is currently no cure for PD, but there are treatments available to relieve the symptoms and maintain an individual’s quality of life (QoL) at least for the first years. The PD impact on the QoL is due to an enormous number of motor and non-motor symptoms: bradykinesia, rigidity, tremor, postural instability, reduced gait speed, freezing of gait (FoG), sleep disturbances, depression, psychosis, autonomic and gastrointestinal dysfunction as well as dementia. The majority of patients will develop an increasing number of more complex symptoms over time. The treatment in the early stages of the disease, focused on the use of levodopa, is very effective. Nevertheless, different problems related to the treatment or disease progression may start to appear depending on the advance of the disease. Thus, it might be the case of motor complications (MCs): motor fluctuations such as the wearing-off phenomenon (temporary loss of dopaminergic effect), involuntary movements known as dyskinesia, fluctuations between the ON stage (when a correct control of the symptoms is achieved) and the OFF stage (when motor symptoms reappear), abnormal cramps and postures of the extremities and trunk known as dystonia, and a variety of complex fluctuations in other motor and nonmotor functions, the nonmotor complications (NMCs). In these cases, the precise adjustment of the therapy is crucial to avoid decreasing the QoL of the patient. The motor symptoms are especially responsible for falls and gait impairments and neg­atively impact on QoL by reducing the ability to perform many activities of daily living. They are the major causes of institutionalization and by the way, losing independence. Daily tasks at home (self-care, food preparation, climb­ing stairs...) become difficult, as do many activities outside the home such as shopping, visiting friends/family, leisure activities, among others. The management of this disease must be multidimensional. Unfortunately, there is often no integration between data at different levels of the health system: primary health physicians, occupational therapists, and social workers. Information about the general condition of the patient is also usually lacking.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

610 AVI a

Penerbit

London : Taylor & Francis., 2024

Deskripsi Fisik

269 hlm

Bahasa

English

ISBN/ISSN

9781032632865

Klasifikasi

610

Tipe Isi

text

Tipe Media

computer

Tipe Pembawa

online resource

Edisi

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Subjek

Medicine and Health, Parkinson

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

Lampiran Berkas

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