Oligonucleotides are short single-stranded sections of DNA orRNA that contain 20-deoxyribo-nucleosides or ribo-nucleosides,respectively, which are linked by 30–50phosphodiester linkages(Fig.1a). Antisense oligonucleotides are those that are complemen-tary to a section of naturally occurring RNA, such as an mRNA or aviral RNA, to form Watson–Crick base pairs and to thus inhibit abiological f…
There is a large and mostly unmet global need for affordable and efficacious wound care, despite modern-day medicine advancing at break-neck speed. Indeed, the tide of chronic wounds is rising. Modern lifestyle changes, particularly in low- and middle-income countries (LMICs), bring a rapid rise in non-communicable disease including cardiovascular disease, o…
It is hard to believe that it has been 14 years since the first edition of Step-Up to Medicine was published. Now in its fifth edition, the success of this book has always been linked to its in-depth, yet concise coverage of every medical topic that a student will encounter during the clinical years of medical school and corresponding NBME shelf examinations. This fifth edition of Step-Up to Me…
In the history of religions, tasks such as curing bodily ailments, treating the sick, and dealing with dying were often assigned to religious experts. Con-cepts such as the body, illness, and health were anchored in the world views and practices of the respective religious traditions. As Pamela Klassen (2016: 401) writes: “Medical knowledge and techniques have often emerged di-rectly…