Currently, the origins ofin vitrocell lines are highly biased towards humans.Around 75% of the total number of established cell lines are from Hominidae origin(96,862/128,799) and over 97% are of mammalian origin (126,033/128,799) (Bairoch2018) (Figure 1). However, mammals represent only 0.4% (1.3% when excluding theInsecta taxon) of the extant identified metazoan evolution (Zhang 2013; Wilson …